Epilepsy

Epilepsy is a general term used for a group of disorders that cause disturbances in electrical signaling in the brain. An epileptic seizure occurs when these energy pulses come much more rapidly due to an electrical abnormality in the brain. This brief electrical surge can happen in just a small area of the brain, or it can affect the whole brain. Depending on the part of the brain that is affected, the surge of electrical energy can cause changes in a person's sensations or state of consciousnes, and uncontrolled movements of certain parts of the body or of the whole body. These changes are known as an epileptic seizure. Epileptic seizures vary in severity and frequency. A seizure is a symptom of epilepsy, but not all seizures are caused by epilepsy.

News items related to the topic: Epilepsy

Protein ‘clumping’ linked to severe form of genetic epilepsy
Researchers at Vanderbilt University for the first time have demonstrated in a mouse model that aggregation, the “clumping together” of abnormal proteins, can contribute to a severe form of genetic epilepsy.

New clues emerge in rare form of childhood epilepsy
Researchers at Vanderbilt University Medical Center (VUMC) are one step closer to understanding what causes early-onset epileptic encephalopathy, a rare form of childhood epilepsy that is difficult to treat and has poor developmental outcomes.

Grants related to the topic: Epilepsy

  • GABA(A) Receptor Assembly/Trafficking/Function and Epilepsy Missense Mutations
    PI: Macdonald, Robert
  • MRI Structural and Functional Connectivity Changes in Temporal Lobe Epilepsy
    PI: Morgan, Victoria

People related to the topic: Epilepsy

Kevin Ess, M.D., Ph.D.
Gerald M. Fenichel Chair in Neurology; Associate Professor of Pediatrics, Cell & Developmental Biology, and Neurology; Director, Division of Pediatric Neurology

Kevin Haas, Ph.D., M.D.
Assistant Professor of Neurology

Peter Hedera, M.D.
Assistant Professor of Neurology

Robert L. Macdonald, M.D., Ph.D.
Margaret and John Warner Professor of Neurology; Professor of Pharmacology and Molecular Physiology and Biophysics

Beth Malow, M.D., M.S.
Burry Chair in Cognitive Childhood Development; Professor of Neurology and Pediatrics; Director, Vanderbilt Sleep Disorders Division

Victoria Morgan, Ph.D.
Associate Professor of Radiology & Radiological Sciences and Biomedical Engineering

James Sutcliffe, Ph.D.
Associate Professor of Molecular Physiology & Biophysics and Psychiatry & Behavioral Sciences

David Zald, Ph.D.
Professor of Psychology and Psychiatry & Behavioral Sciences

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