Overview of Interests
Dr. Lewis' research focuses on understanding the neurobiology underlying social impairments across neuropsychiatric disorders, with an emphasis on development of novel treatments for aggressive behaviors arising within neurodevelopmental conditions. Toward this goal,he uses animal models and systems neuroscience approaches to identify brain regions and circuits that modulate social and aggressive behaviors. Dr Lewis has recently begun collaborative efforts to incorporate genetic data, including whole exome sequencing, from cohorts of individuals with autism spectrum disorder to gain further specificity in understanding pathways related to aggression in this population. His work involves direct translation of basic research findings into early clinical studies to explore mechanisms in humans, with the goal being to support future, more comprehensive evaluation of treatment modalities.
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