Core Services for Vanderbilt Kennedy Center Investigators
The Vanderbilt Kennedy Center is funded as a Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center (IDDRC) by the Eunice Kennedy Shriver National Institute of Child Health and Human Development to advance the diagnosis, prevention, treatment, and amelioration of intellectual and developmental disabilities (IDD). It is part of the network of 15 national IDDRCs.
The VKC IDDRC focuses on elucidating mechanisms and interventions for persons with autism spectrum disorder, learning disabilities, genetic syndromes, and acquired and general IDD. The VKC IDDRC cores facilitate interdisciplinary and translational research in IDD and support IDD-related projects funded by other sources. Cores meet the needs of investigators and also generate novel technologies, tools, or resources that drive innovative discoveries aimed at understanding and ameliorating IDD.
The pages in this section provide details and contact information for core services.
Overview of IDDRC Cores
Click on the support core of interest for a more detailed service list
Administrative Core (A)
Provides scientific leadership and oversight of the IDDRC, its cores, and IDDRC research project. Manages fiscal and other resources. Coordinates IDDRC Training and Education. Coordinates communication activities to promote IDDRC cohesiveness and collaboration within IDDRC and IDDRC network. Disseminates research findings. Services are (a) governance and oversight, (b) fiscal and resource management, (c) space and facilities, (d) technical services, (e) training, education, and communications.
Clinical Translational Core (B)
Provides a service bridge between basic and clinical scientists who aim to advance the translational impact of their research on neurodevelopmental disabilities. Services are (a) recruitment, (b) registries and epidemiological databases and mining, (c) neurobehavioral phenotyping and outcomes, (d) facilitating clinical trials.
Translational Neuroimaging Core (C)
Provides facilities and services to support individual neuroimaging research programs. Develops novel data acquisition and analysis methods. Uses repositories of VU “big data” to develop new IDD tools and discoveries. Facilitates interdisciplinary collaborations among investigators with varying levels of neuroimaging expertise. Services are (a) access to MRI/fMRI/EEG/ERP data acquisition and analysis methods, (b) assistance with study design, mock scanning, and obtaining pilot data (EEG/ERP), (c) development of pipeline analyses for investigators.
Neuroscience Core (D)
Provides training, facilities, services to support individual neuroscience research programs. Facilitates interdisciplinary collaborations. Develops, tests, delivers access to emerging neuroscience technologies. Service cores are (a) mouse behavioral phenotyping, (b) neurochemistry, (c) molecular neurobiology and genomics, (d) scientific instrumentation.
Biostatistics and Bioinformatics (E)
Provides statistical consultation in experimental design, efficient data collection and storage, statistical analysis, and interpretation of findings. Develops bioinformatics platforms for automation of data processing from multiple sources and implementation of less used or novel data analysis approaches in IDD research. Develops EMR and genomic databases in a range of IDD conditions, with related training and support. Services are (a) assistance with statistical design and analysis, and educational workshops, (b) development of platforms to integrate multiple data sources.
Sensory and Multisensory Contributions to Autism (IDDRC Research Project)
Mark Wallace, Ph.D., Principal Investigator