Core Services for Vanderbilt Kennedy Center Investigators
The Vanderbilt Kennedy Center is funded as a Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center (IDDRC) by the Eunice Kennedy Shriver National Institute of Child Health and Human Development to advance the diagnosis, prevention, treatment, and amelioration of intellectual and developmental disabilities (IDD). It is part of the network of 15 national IDDRCs.
The Vanderbilt Kennedy Center IDDRC provides core services to enable and disseminate impactful research on the causes, mechanisms, and treatment of intellectual and developmental disabilities (IDD). IDD research at Vanderbilt is enabled by the IDDRC core services that provide impactful, needed, cost-effective, non-duplicative, and innovative services, and are also generative of new approaches or services.
The pages in this section provide details and contact information for core services.
Overview of IDDRC Cores
Click on the support core of interest for a more detailed service list
Administrative Core (A)
Core A provides1) overall oversight and management of the IDDRC cores and the research project, 2) oversees interactions with internal, external, and community advisory committees, 3) coordinates training and educational activities, 4) oversees pilot grant funding, and 5) provides all IDDRC communication, dissemination, and implementation services.
Clinical Translational Core (B)
Core B enables and encourages clinical research to accelerate the translation of basic discoveries into meaningful IDD interventions. The core bridge sto VUMC’s extensive infrastructure to conduct clinical research by assisting in recruitment and maintaining research registries and enhancing IDDRC Investigator use of extensive electronic medical records, biorepositories, and systems to enable pragmatic trials, as well as focused efforts on increasing inclusion of IDD populations into ongoing clinical research.
Translational Neurosciences Core (C)
Core C creates and improves technology to facilitate and streamline neuroimaging and neurophysiological data acquisition and analysis in people with IDDs and in rodent models of IDD. This provides an essential platform for ongoing and future research studies that link neural and behavioral functioning within and across diverse IDD, and for trans-species comparisons. The core supports both novice and experienced users who aim to includeneuroimaging or neurophysiology in their studies.
Behavioral Phenotyping Core (D)
Core D provides comprehensive behavioral and physiological assessments for both people with IDD and rodent models of IDD, with a focus on trans-species approaches and developing novel methods. Newly added is assessment of physiological features in free moving mice. Human phenotyping provides expert consultations on clinical trial outcome measures, full-service human behavioral phenotyping, and assessment methods needed; it also consults on the development of novel methods for assessing minimally verbal people, parent-based behavioral assessments, or human physiological assessments using wearable devices.
Data Sciences Core (E)
Core E combines traditional data analysis approaches (statistics) with newer methods for data analysis to enhance IDD research. This core enables and supports comprehensive data analysis and facilitates novel data sciences approaches to propel new directions for IDDRC investigators. Core faculty work to increase interactions with VU’s Data Sciences Institute and to expand the use of advanced techniques such as machine learning and natural language processing. The core oversees an innovative training program to encourage data scientists to engage with IDD research and to enable IDD researchers access to modern data sciences approaches. Core E also houses a de-identified electronic medical record IDD-curated database to provide IDD researchers a resource for IDD studies and preliminary data.
IDDRC P50 Research Project
Antipsychotic-induced Weight Gain in Autism Spectrum Disorder